Homocysteine Interpreter.
Homocysteine links B-vitamin status to cardiovascular and cognitive risk. "Normal" labs accept up to 15, but optimal is lower. Enter yours to see where you land.
A modifiable marker of methylation and risk.
Homocysteine is an amino acid your body clears using vitamins B12, folate, and B6. When those run low — or when an MTHFR gene variant slows the pathway — homocysteine accumulates. Elevated levels are associated with higher cardiovascular and cognitive risk, and the legacy lab cutoff (under 15 µmol/L) is looser than the under-7-to-10 that prevention-focused clinicians prefer.
The practical value is that it is highly modifiable: repleting B12 and folate (methylated forms if you carry an MTHFR variant) usually lowers homocysteine within weeks. Just treat it as one input among many — kidney disease, hypothyroidism, smoking, and some medications also raise it, and trials show the clearest cognitive benefit from lowering it in people who also have adequate omega-3 status.
Homocysteine responds to B-vitamin–rich, nutrient-dense food. Start with the blueprint's fundamentals chapter.
Get the guide →For education, not medical advice. Results are estimates, not a diagnosis — discuss any abnormal value or health concern with a qualified clinician.
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