Homocysteine Interpreter.

Homocysteine is an amino acid your body clears using vitamins B12, folate, and B6. When those run low — or when an MTHFR gene variant slows the pathway — homocysteine accumulates. Elevated levels are associated with higher cardiovascular and cognitive risk, and the legacy lab cutoff (under 15 µmol/L) is looser than the under-7-to-10 that prevention-focused clinicians prefer.

The practical value is that it is highly modifiable: repleting B12 and folate (methylated forms if you carry an MTHFR variant) usually lowers homocysteine within weeks. Just treat it as one input among many — kidney disease, hypothyroidism, smoking, and some medications also raise it, and trials show the clearest cognitive benefit from lowering it in people who also have adequate omega-3 status.