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Tool / Longevity

TyG Index Calculator.

The triglyceride-glucose index estimates insulin resistance from two numbers on any standard lipid panel — no insulin test needed. Enter your fasting triglycerides and glucose.

mg/dL — after 8+ hours fasting

mg/dL — same blood draw

The Science

Insulin resistance without an insulin test.

HOMA-IR is the usual home-lab insulin-resistance marker, but it needs a fasting insulin value — which many standard panels skip. The triglyceride-glucose (TyG) index solves that: it estimates insulin resistance from just fasting triglycerides and fasting glucose, both of which are on virtually every lipid panel. TyG = ln(triglycerides × glucose / 2), with the two values in mg/dL.

It holds up well. Validated against the gold-standard euglycemic clamp, a TyG of about 8.5 flagged insulin resistance with ~83% sensitivity and specificity (Guerrero-Romero 2010). Higher TyG also tracks independently with arterial stiffness, fatty liver, and cardiovascular events — so it doubles as a cheap metabolic-risk read.

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